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COVID-19 Vaccine update: The race to save mankind




Each country is racing to develop the cure to this global pandemic . A lot of super powers except the US have already pledged to forward 8million dollars towards the research, manufacturing and supply of the vaccine apart from their individual research. Here is a look into where the individual researches of these countries to develop the COVID-19 vaccine has reached.



United Kingdom

Scientists at the Jenner Institute of Oxford University have stated to have made a potential vaccine for coronavirus. The vaccine is being developed with multiple partners including the Serum Institute of India. Two volunteers were injected, the first of more than 800 people recruited for the study. The vaccine was developed in under three months by a team at Oxford University. Sarah Gilbert, professor of vaccinology at the Jenner Institute, led the pre-clinical research. A larger trial, of about 5,000 volunteers, will start in the coming months and will have no age limit.

Interferon Beta, a drug developed by biotech company Synairgen has been injected in patients as part of initial trials. Used for treating multiple sclerosis, the results of the Interferon Beta injection will be delivered by June.

Italy

Takis, the firm developing the COVID 19 vaccine, has been able to demonstrate neutralization of coronavirus by a vaccine. The candidate was a mice. Human tests for the vaccine are expected after this summer.


India

Around 30 vaccines are under different stages of development in India.

India’s pharmaceutical companies working on at least 3 vaccines with US according to India’s ambassador Taranjit Singh Sandhu. According to a WHO document, Indian companies like Zydus Cadila, Codagenix-Serum Institute of India, Indian Immunological with Griffith University, Bharat Biotech in association with Thomas Jefferson University, Biological E Ltd, and the UW Madison-FluGen-Bharat Biotech combine are all working on potential vaccine candidates to cure the coronavirus infection.


Israel

According to the Defence Minister of Israel, Naftali Bennett, the Israel Institute for Biological Research (IIBR) has developed an antibody to neutralise the COVID-19 virus. It can attack the virus within the bodies of the infected and neutralise it.

Testing on rodents was being conducted since last month. Another research team, MigVax has completed the first phase of developing the COVID-19 vaccine and has secured a $12 million investment to develop the vaccine. There is no information yet on human testing.


China

China has approved three coronavirus vaccines, including the one developed by Chinese military, the People’s Liberation Army (PLA) for clinical trials

An adenovirus vector vaccine, developed by Institute of Military Medicine under the Academy of Military Sciences, was the first to be approved to enter a clinical trial.

The first phase of the clinical trial was completed at the end of March, and the second phase started on April 12.

Prior to this, PiCoVacc, an inactivated COVID 19 vaccine candidate made by Beijing-based Sinovac Biotech, has shown promising results as the experimental vaccine could help protect the rhesus macaques, a type of monkey originating in India, from the virus.Sinovac was previously developing a vaccine against SARS, a pandemic which originated in China back in 2003 and is caused by a type of coronavirus.


United States

US pharmaceutical major Pfizer and its German partner BioNTech SE said on May 5 that they have already begun delivering doses of their coronavirus vaccine to candidates for initial human testing in USA. Trials have also begun in Germany. Even though the drug s still under testing, pfizer is readying plans to manufacture millions of vaccine doses in 2020.

Gilead Sciences has developed Remdesivir, a broad-spectrum antiviral medication that is being tested as a specific treatment for COVID-19 infections. The drug has been authorised for emergency use in USA and has been also approved for use in Japan for people with severe symptoms of coronavirus infection. Another pharmaceutical company, Regeneron stated that its 'anti-body' treatment drug could also be available by September. Moderna, Johnson & Johnson, and several other biopharmaceutical companies have also ramped-up efforts to develop a COVID-19 vaccine. Johnson & Johnson is working with Biomedical Advanced Research and Development Authority (BARDA).

US Vice-President said that 4.93 million coronavirus tests have been completed across the US, adding that commercial labs have surpassed 100,000 tests.




Source: businesstoday.in , indiatimes.com , bbc.com , livening.com , moneycontrol.com .


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